From Atomic Structures to Neuronal Functions of G Protein–Coupled Receptors
نویسندگان
چکیده
منابع مشابه
From atomic structures to neuronal functions of g protein-coupled receptors.
G protein-coupled receptors (GPCRs) are essential mediators of signal transduction, neurotransmission, ion channel regulation, and other cellular events. GPCRs are activated by diverse stimuli, including light, enzymatic processing of their N-termini, and binding of proteins, peptides, or small molecules such as neurotransmitters. GPCR dysfunction caused by receptor mutations and environmental ...
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ژورنال
عنوان ژورنال: Annual Review of Neuroscience
سال: 2013
ISSN: 0147-006X,1545-4126
DOI: 10.1146/annurev-neuro-062012-170313